BASIC INDUSTRIAL BIOTECHNOLOGY Question Papers (Regular, 2005)

SET: 1

1. Briefly write a historical overview of Industrial fermentation process.

2. Describe the necessity of inoculum development in fermentation process?

3. Explain the production of acetic acid by fermentation with the help of a diagram?

4. Define aromatics

Describe the properties of aromatic compounds.

Give the outline details of biotechnological production of aromatic compounds.

5. Write the importance of enzymes in economizing the industrial development?

6. Enumerate the importance of primary metabolite production in continuous culturing conditioning?

7. Give detailed account of polyhydroxybutyrate, production by microbial systems starting from glucose as carbon source?

8. Write the importance of biological systems in steroids transformations with respect to chemical transformations?

SET: 2

1. Describe the connective links for the production of the following:

(a) Glycolysis – acetic acid production

(b) TCA Cycle – amino acid production

(c) Pyruvic acid – lalctic acid production

2. Briefly describe the over production methodologies used in fermentation industry?

3. Describe the recovery process of gluconic acid from fermentation broth with the help of flow sheet?

4. Enumerate the role of precursors and inducers in secondary metabolites production?

5. Write short notes with examples on:

6. Indicates the importance of feed back inhibition in bio-product production with examples ?

7. Give detailed account of polyhydroxybutarate production by microbial system starting from glucose as carbon source?

8. Give the importance of recombinant DNA technology in viral vaccine development?

SET: 3

1. Describe the connective links for production of following:

(a) Glycolysis – acetic acid production

(b) TCA Cycle – amino acid production

(c) Pyruvic acid – lalctic acid production

2. Give an account on production and bi-products that could be as substrates in biotech industries?

3. Describes the role of anaerobic fermentation process in the production of organic acids?

4. Enumerate the importance of recombinant proteins in human health care sector?

5. Discuss the importance of recombinant proteins in human healthcare sector?

6. (a) Describe somatic hybridization with examples?

(b) Bring out the uses of protoplast fusion and somatic hybrids?

7. List out and describe some useful microbes that can be used as bio-pesticides?

8. What is the importance of interferon in human health care and illustrate their production processes?

SET: 4

1. Write the importance of the following in bioprocess development:

(a) Microbiological inputs.

(b) Bio reactor operation modes.

(c) Process parameters.

2. What are the important criteria to select the agricultural waste materials as raw material for fermentation?

3. Describe the role of anaerobic fermentation process in the production of organic acids?

4. Write the importance of production medium in antibiotic production by microorganisms?

5. Describe enzyme production by semisolid culture method and mention its advantages and disadvantages?

6. Write short notes:

(a) Various steps involved in auxotrophic selection.

(b) Importance of metabolic flow redirection in product production.

7. Give detailed account of polyhydroxybutarate production by microbial system starting from glucose as carbon source?

8. Write short notes on :

(a) Difference between vaccine and antibody.

(b) Immune response and vaccines.

(c) Disease control by vaccination.