BIOAFFINITY BASED BIOSENSORS

Based on the Biological Material used they can be classified into 2 categories:

• Antibody based biosensors
• Nucleic acid based biosensors

Antibody based Biosensors:

Also called as immunosensors.
Use Monoclonal and Polyclonal Antibodies.
Advantages:

• They are ultra sensitive
• Very Selective

Nucleicacid based biosensors:

Specific pairing abilities of the nucleic acids are exploited.
Aptamer Beacons are a recent innovation in Biosensor technology. They are oligonucleotide sequences that bind specifically to non-nucleotide target molecules like proteins, steroids etc. We can configure the aptamer beacons to bind specifically to a particular analyte.