BIOLOGICAL PHARMACY Question Papers 4 A.U

Answer question no.1(compulsory) and any four of the remaining. All questions carry equal marks

1. Write notes on:

• Schick test and Schick control
• Urokinase
• Heparin
• Dextran 40

2. Describe the general requirements for blood collection, preparation, storage, labeling and uses of whole human blood. Add notes on concentrated RBC's.

3. Describe in brief:

• Purified protein derivative.
• Mantoux test.
• PVP
• Oxidised cellulose

4. What are active immunising agents? Classify them. Describe the manufacture and standardization of small pox vaccine.

5. Write about:

• Diphtheria toxoid and different formulation adjuvants used in its manufacture. Add notes on the advantages
• Antirabies serum
• Antivenoms

6. What is 'Test for Sterility'? Describe the general protocol. Explain the rational of different controls. Add notes on the sterility testing of catgut.

7. Write the principle, advantages, limitations of microbiological assays. Add notes on the different types of assays. Explain the terms 'One level' and 'two level' factorial assays.

8. Write about the following in brief:

• Prostaglandins
• Pancreatin
• Ligatures and Sutures
• DPT